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Health & Nutrition

Metabolic Syndrome/Insulin Resistance

  • Metabolic disease/disorder: Metabolism is the process body uses to get or make energy from the food we eat. A metabolic disorder occurs when abnormal chemical reactions in the body disrupt this process. There are different types of metabolic disorders; some affect the breakdown of amino acids, carbohydrates or lipids and some are mitochondrial diseases that affects cell’s energy production. One can develop a metabolic disorder when organs, such as liver or pancreas, become diseased or do not function normally (e.g.: diabetes and fatty liver disease).

Some experts consider these disorders also metabolic diseases: brain disease such as Alzheimer and Parkinson’s disease as well as disease with inflammatory and autoimmune root cases such as IBD (Irritable bowl disease; ulcerative colitis & crohn’s disease), EoE (Eosinophilic esophagitis) and skin disorders such as Atopic dermatitis (eczema) and Psoriasis. 

  • Metabolic syndrome: A group of conditions that will increase the risk for heart disease and diabetes. These conditions are:
    • High blood pressures
    • High blood glucose, or blood sugar, levels
    • High levels of triglyceride, a type of fat, in blood
    • Low levels of the good cholesterol, in blood
    • Too much fat around waist 

Other definitions

  • Insulin: Hormone produced in the pancreas by the islets of Langerhans, which regulates the amount of glucose in the blood. The lack of insulin causes a form of diabetes. An animal-derived or synthetic form of insulin used to treat diabetes.
  • Insulin resistance: An impaired response of the body to insulin, resulting in elevated levels of glucose in the blood (a key component of type 2 diabetes and metabolic syndrome). Scientifically, Insulin resistance is defined clinically as the inability of a known quantity of exogenous (insulin people inject or infuse via an insulin pump) or endogenous insulin (insulin the pancreas makes) to increase glucose uptake and utilization in an individual as much as it does in a normal population.

References:

https://medlineplus.gov/metabolicdisorders.html

https://www.ncbi.nlm.nih.gov/pubmed/11460565

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362431/

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